Purity of Zinc Sulfate (J. P.) as Pharmaceutical Aid

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  • 製剤原料としての局方硫酸亜鉛の純度

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Abstract

White Lotion became gray suspension when it was prepared from Zinc Sulfate (J. P., Lot No.S3853C) as pharmaceutical aid. It was found that the coloration was caused by 195 ppm of Ni detected as impurities in Zinc Sulfate in the test conducted in compliance with Atomic Absorption Spectrophotometry (J. P. IX) and Spectrophotometry of Ni with Dimethylglyoxime, though it was not clarified in a test in compliance with J. P. IX. The change in color of White Lotion was caused by black Nickel Sulfide precipitated after the formation of white Colloidal Sulfur and white Zinc Sulfide.

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