Ｃｉｓａｐｒｉｄｅにより発現した錐体外路症状の１症例

• 太田 伸

  信州大学医学部附属病院薬剤部

• 伊藤 充

  信州大学医学部附属病院薬剤部

• 跡部 治

  信州大学医学部附属病院薬剤部

• 全田 浩

  信州大学医学部附属病院薬剤部

書誌事項

タイトル別名

• Case Study of Extrapyramidal Syndrome Apparently Due to Cisapride.

抄録

Cisapride is a widely used drug which stimulates gastrointestinal motility. We report a case of extrapyramidal syndrome apparently caused by cisapride. In November, 1993, a 77-year-old female patient had symptoms of tremor, stiffness and numbness. She had been receiving 15 mg/day of cisapride since June 1993. Additionally, the patient was receiving 10 kinds of medications.<BR>Cisapride was discontinued in December 1994. Two months later, the above-noted symptoms disappeared. Cisapride acts selectively on the myenteric plexus of the digestive tract, and enhances the release of acetylcholine. It has been reported that cisapride has neither an antidopaminergic nor a nonspecific cholinergic property. For these reason, it is believed that cisapride did not induce these side effects. However, the above case of extrapyramidal syndrome apparently caused by cisapride shows that cisapride should be used carefully especially with regards to the potential neurological side effects.

収録刊行物

• 病院薬学

  病院薬学 22 (4), 364-368, 1996

  一般社団法人 日本医療薬学会

キーワード

• cisapride
• extrapyramidal syndrome
• tremor
• stiffness
• numbness

詳細情報

• CRID: 1390001204774621440
• NII論文ID: 110001799590
• NII論文ID: 130004103140
• NII書誌ID: AN00002794
• DOI: 10.5649/jjphcs1975.22.364
• ISSN: 21859477
• ISSN: 03899098
• Web Site: http://dl.ndl.go.jp/info:ndljp/pid/10561786
• Web Site: https://search.jamas.or.jp/link/ui/1997032398
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • NDL-Digital
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可