外来患者におけるテオフィリンの TDM に対する医師の意識調査  [in Japanese] An Attitude Surveillance of Physicians for Therapeutic Drug Monitoring of Theophylline in Outpatients  [in Japanese]

Investigation of the actual conditions and attitude surveillance of physicians to ward therapeutic drug monitoring (TDM) of theophylline were performed in outpatients prescribed a control released theophylline-tablet (Theodur^<[O!R]>) in November 1996. TDM of theophylline was performed in 1.6% of patients to whom were prescribed Theodur^<[O!R]> during this period. The ratio of the patients who had a TDM history of theophylline was 28.1% of all patients prescribed Theodur^<[O!R]>). while it was 41.7% in patients receiving over the usual Theodur^<[O!R]> dose range (400 mg/day). Most physicians recognized the benefit of TDM, while about a half considered that TDM of is not essential for patients taking more than 400 mg,/day of the drug when their clinical condition is stable.