EFFECTS OF EXHAUSTIVE EXERCISE ON SARCOPLASMIC RETICULUM ATPase

DOI IR Web Site Web Site 1 Citations 23 References Open Access

Bibliographic Information

Other Title
  • 疲労困憊に至る運動が筋小胞体ATPaseに及ぼす影響
  • 疲労困憊に至る運動が筋小胞体ATPaseに及ぼす影響--短時間運動と長時間運動の比較
  • ヒロウ コンパイ ニ イタル ウンドウ ガ キン ショウホウタイ ATPase
  • —COMPARISON OF SHORT- AND LONG-TERM EXERCISE—
  • ―短時間運動と長時間運動の比較―

Search this article

Abstract

Effects of short-term, high-intensity and long-term, moderate-intensity exercise on biochemically assessed sarcoplasmic reticulum (SR) ATPase protein were analyzed in muscle homogenates of the rat after treadmill runs to exhaustion (avg, time to exhaustion 2 min 48 sec and 1 h 29 min, respectively) . The exercise-induced changes in SR Ca2+ -ATPase activity were muscle type-specific. After short-term exercise, a decrease in the activity occurred in the soleus muscle and the superficial region of the vastus lateralis muscle whereas long-term exercise depressed the rate of ATP hydrolysis in the soleus muscle and the deep region of the vastus lateralis muscle. The concentration of fluorescein isothiocyanate, a competitor at the ATP-binding site, for 50% inhibition of SR Ca2+ -ATPase activity fluctuated only in the soleus muscle subjected to short-term exercise ; it was increased by 31%. This change occurring in the soleus muscle would elevate SR Ca2+ -ATPase activity at a given concentration of ATP. The results presented here suggest that acute short-term exercise to exhaustion may exert a remarkably inhibitory factor on SR Ca2+ -ATPase protein of slow-twitch muscle, which can overcome the positive effect probably arising from the phosphorylation of the phospholamban.

Journal

Citations (1)*help

See more

References(23)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top