神経芽腫の国際病期分類 International Neuroblastoma Staging System (INSS)  [in Japanese] Introduction of the International Neuroblastoma Staging System (INSS)  [in Japanese]

    • 金子 道夫 Kaneko Michio
    • 筑波大学臨床医学系小児外科 Department of Pediatric Surgery, Institute of Clinical Medicine, University of Tsukuba

Access this Article

  • CiNii Fulltext PDF

    Subscription

Search this Article

Abstract

一つの疾患に対して大規模なグループスタディが広く行われ,その治療成績や予後因子を比較するとき,臨床病期分類が国際的に統一されていないことは非常に大きな問題である.そこで,神経芽腫においては病期分類の国際統一にむけて欧米の各国の参加のもとに INSS(International Neuroblastoma Staging System) の確立を目指して討議が行われ, 1988年に INSS 分類が Journal of Clinical 0ncology に掲載された.この分類は国際的に急速に普及しており,今後の神経芽腫の治療や研究に必須事項になったと考えられる. INSS 分類の特徴はこれまでわが国の小児固形腫傷病期分類にはなかった resectability を取り入れていることであり,手術を行う外科医の分類に対する理解が不可欠である.わが国での本分類の理解と普及にむけて,その骨子とポイントを,特に外科医にも理解しやすいように解説し,手術後,分類が容易かつ誤りがないようにした.また併せて同時に検討された効果判定基準,リスク分類についても報告した.

There have been a variety of staging systems and their modifications to classify the extent of neuroblastoma, and different criteria have been used to determine the response to therapy. These differences have brought us much difficulties to compare the results of clinical trials and basic researches performed in different groups or in different countries. In Japan, the staging system of the pediatric solid tumors was established by the Committee on the Tumor Registration of the Japanese Society of Pediatric Surgeons and currently used as a sole nation-wide system. Its staging for neuroblastoma has a close similarity to Evans' staging system. In 1986, a meeting was held to establish an international criteria for neuroblastoma diagnosis, staging and response to treatment (INSS and INRC) which was published in the Journal of Clinical Oncology in 1988. The criteria represent an international consensus of essentially every major pediatric oncology group or organizations in the United States, Europe and Japan. The criteria were widely accepted in the world and have become absolutely essential for presenting papers in scientific meetings and publication. This paper was written for a better understanding and further spreading of INSS in Japan and with a hope for INSS to being adopted for the Tumor Registry in Japan.

Journal

Journal of the Japanese Society of Pediatric Surgeons   [List of Volumes]

Journal of the Japanese Society of Pediatric Surgeons 33(2), 249-255, 1997-04-20  [Table of Contents]

The Japanese Society of Pediatric Surgeons (JSPS)

References:  7

You must have a user ID to see the references.If you already have a user ID, please click "Login" to access the info.New users can click "Sign Up" to register for an user ID.

Cited by:  4

You must have a user ID to see the cited references.If you already have a user ID, please click "Login" to access the info.New users can click "Sign Up" to register for an user ID.

Codes

  • NII Article ID (NAID) :
    110002085720
  • NII NACSIS-CAT ID (NCID) :
    AN00192281
  • Text Lang :
    JPN
  • Article Type :
    Journal Article
  • ISSN :
    0288609X
  • Databases :
    CJP  CJPref  NII-ELS