鎖肛に関する基礎的研究 : I.実験モデルとしての鎖肛ブタの検討  [in Japanese] Basic Studies on the Anorectal Malformations : ?. An Examination of swine as an experimental animal medel  [in Japanese]

For the purpose of investigating the possibility to establish an experimental animal model, the anorectal malformations of swine was studiea The questionaires were sent to 404 swineries in order to know the actual occurrence of imperforate anus in swines. The statistical analysis on their reports revealed that an imperforate anus was indemnified per 566.6 swine deliveries (the incidence was 0.81%), and that those anomalies had predominant tendency in hereditary occurrence. Close similarities were also demonstrated between swine and human being in the types of anorectal malformations. In conclusion, those swine with imperforate anus can be used as an appropriate experimental animal model and they are considered to be very useful material for studying the pathogenesis and for devising the treatment method of human anorectal malformations.