Subclinical Carpal Tunnel Syndrome in Acromegaly KAMEYAMA Shigeki TANAKA Ryuichi HASEGAWA Akira TAMURA Tetsuro KUROKI Mizuo 日本脳神経外科学会 Neurologia medico-chirurgica 04708105 33 8 547 551 1993-08-15 Median nerve conduction was studied in 16 acromegalic patients with asymptomatic carpal tunnel syndrome (CTS) to examine the incidence of subclinical CTS. Thirteen patients (81%) and 23 hands (72%) demonstrated subclinical CTS, 10 bilaterally and three unilaterally in the dominant hand. The incidence reflects the greater sensitivity of the inching method for detecting focal conduction abnormalities. Two of three patients without subclinical CTS showed normal plasma somatomedin-C concentration despite growth hormone hypersecretion. Following adenomectomy, nerve conduction normalized in only six hands (26%). The postoperative persistence of the conduction delay implies that irreversible narrowing of the carpal tunnel rather than reversible soft tissue edema is the principal cause of CTS associated with acromegaly. 1993-08-15 110002278460 AN00358613 ENG NII-ELS Journal@rchive 3 Subclinical Carpal Tunnel Syndrome in Acromegaly KAMEYAMA Shigeki TANAKA Ryuichi HASEGAWA Akira TAMURA Tetsuro KUROKI Mizuo The Japan Neurosurgical Society 神経外科 Median nerve conduction was studied in 16 acromegalic patients with asymptomatic carpal tunnel syndrome (CTS) to examine the incidence of subclinical CTS. Thirteen patients (81%) and 23 hands (72%) demonstrated subclinical CTS, 10 bilaterally and three unilaterally in the dominant hand. The incidence reflects the greater sensitivity of the inching method for detecting focal conduction abnormalities. Two of three patients without subclinical CTS showed normal plasma somatomedin-C concentration despite growth hormone hypersecretion. Following adenomectomy, nerve conduction normalized in only six hands (26%). The postoperative persistence of the conduction delay implies that irreversible narrowing of the carpal tunnel rather than reversible soft tissue edema is the principal cause of CTS associated with acromegaly. KAMEYAMA Shigeki Department of Neurosurgery, Brain Research Institute, Niigata University TANAKA Ryuichi Department of Neurosurgery, Brain Research Institute, Niigata University HASEGAWA Akira Department of Neurosurgery, Brain Research Institute, Niigata University TAMURA Tetsuro Department of Neurosurgery, Brain Research Institute, Niigata University KUROKI Mizuo Department of Neurosurgery, Brain Research Institute, Niigata University