Positron Emission Tomography:特に脳腫瘍症例における<SUP>68</SUP>Ga-EDTA Positron Emission Tomographyを中心として

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  • Positron Emission Tomography with Positome II: With Special Reference to <SUP>68</SUP>Ga-EDTA Positron Emission Tomography in Cases with Brain Tumor

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Positron emission tomography with Positome II using 66Ga-EDTA was performed in cases with brain tumor and cerebral arteriovenous malformation. A significant focal uptake in static study and hemodynamic changes in dynamic study were noted in all cases except one case with intracranial lipoma.<BR> Comparing this method with 99mTc-pertechnetate cerebral image study and computerized axial tomography, the diagnostic rate for detecting brain tumor was almost equal in all of these three methods. However, detecting and localizing was easier and clearer in static positron emission tomography with 68Ga-EDTA than in 99mTcpertechnetate cerebral image and computerized axial tomography without infusion of contrast medium. Furthermore, static positron emission tomography with 68Ga-EDTA was superior to computerized axial tomography without infusion of contrast medium for detecting cerebral arteriovenous malformation.<BR> Concerning dynamic positron emission tomography with 68Ga-EDTA, semiquantitative values obtained by this method correlated well with findings of computerized axial tomography and was thought to be more precise and in detail than the findings of 99mTc-pertechnetate cerebral image study.<BR> Summation of the previous studies about dynamic positron emission tomography with 77Kr in occlusive cerebrovascular disease is also reported.<BR> In conclusion, static positron emission tomography with 68Ga-EDTA is a very useful diagnostic method for detecting and localizing brain tumor and cerebral arteriovenous malformation without any attendant complications. Furthermore, a good combination of static and dynamic positron emission tomography and computerized axial tomography appear to be outstandingly effective for not only detecting the lesion but also understanding the pathophysiological aspect in cases with various intracranial lesions.

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