CT上神経膠腫との鑑別が困難であった脱髄性疾患の1例 中洲 庸子 須田 金弥 半田 譲二 挟間 章忠 日本脳神経外科学会 Neurologia medico-chirurgica 04708105 22 12 1035 1038 1982-12-15 Demyelinating diseases of the brain may show mass effects and/or contrast enhancement on CT scans, simulating the appearance of infiltrating glioma. A 36-year-old male, had suffered from gait disturbance and convulsive attacks involving the right lower limb since the age of 30. He had gradually developed character changes and urine incontinence. Six months prior to admission he experienced several attacks of generalized convulsions. On admission, he showed a mild hemiparesis, bilateral Babinski signs, and ataxic gait. He was disoriented and had memory disturbance and moria. CT scan showed low density areas in the bilateral frontal lobes and corpus callosum associated with a mild mass effect. Contrast study revealed irregular enhancement along the edge of the low density arca and another small enhancing lesion in the left temporal lobe. This CT finding was interpreted as that of "butterfly" glioma. Craniotomy and right frontal lobectomy were performed. Histological study, however, demonstrated demyelination in the white matter associated with perivascular proliferation of lymphocytes. The final diagnosis was the 'transitional sclerosis' of Poser. 1982-12-15 110002279319 AN00358613 JPN NII-ELS Journal@rchive 3 Primary Demyelinating Disease Simulating Infiltrating Glioma on CT NAKASU Yoko SUDA Kinya HANDA Jyoji HAZAMA Humitada The Japan Neurosurgical Society 神経外科 Demyelinating diseases of the brain may show mass effects and/or contrast enhancement on CT scans, simulating the appearance of infiltrating glioma. A 36-year-old male, had suffered from gait disturbance and convulsive attacks involving the right lower limb since the age of 30. He had gradually developed character changes and urine incontinence. Six months prior to admission he experienced several attacks of generalized convulsions. On admission, he showed a mild hemiparesis, bilateral Babinski signs, and ataxic gait. He was disoriented and had memory disturbance and moria. CT scan showed low density areas in the bilateral frontal lobes and corpus callosum associated with a mild mass effect. Contrast study revealed irregular enhancement along the edge of the low density arca and another small enhancing lesion in the left temporal lobe. This CT finding was interpreted as that of "butterfly" glioma. Craniotomy and right frontal lobectomy were performed. Histological study, however, demonstrated demyelination in the white matter associated with perivascular proliferation of lymphocytes. The final diagnosis was the 'transitional sclerosis' of Poser. 中洲 庸子 NAKASU Yoko 滋賀医科大学脳神経外科 Department of Neurosurgery,Shiga University of Medical Science 須田 金弥 SUDA Kinya 滋賀医科大学脳神経外科 Department of Neurosurgery,Shiga University of Medical Science 半田 譲二 HANDA Jyoji 滋賀医科大学脳神経外科 Department of Neurosurgery,Shiga University of Medical Science 挟間 章忠 HAZAMA Humitada 滋賀医科大学第二美容理 Department of Neurosurgery,The Second Pathology,Shiga University of Medical Science