Effects of Caffeine on Mitotic Delay of Sea Urchin Eggs Fertilized with X-irradiated Sperm
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- 木村 博
- 東京大学理学部動物学教室
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When sea urchin eggs were fertilized with X-irradiated sperm, the prolongation of streak stage in the first cleavage was induced. Caffeine reduced the prolonged streak stage only when the chemical was administered during the period of the prolongation. This effect of caffeine was observed at the concentrations higher than 0.13 mM and reached the maximum at approximately 2 mM. Other methylxanthines such as theophylline and theobromine, which are generally known to increase c-AMP contents in the cell, exhibited similar effects upon the mitotic delay. On the other hand, aminophylline which is also considered to increase c-AMP level in sea urchin eggs, had not such effect.
収録刊行物
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- Journal of Radiation Research
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Journal of Radiation Research 15 (2), 75-80, 1974
Journal of Radiation Research 編集委員会
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詳細情報 詳細情報について
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- CRID
- 1390282680193275392
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- NII論文ID
- 110002323092
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- NII書誌ID
- AA00705792
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- COI
- 1:CAS:528:DyaE2MXhtFSnsQ%3D%3D
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- ISSN
- 13499157
- 04493060
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- PubMed
- 4413119
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- NDL-Digital
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可