A CASE OF EOSINOPHILIC CELLULITIS (WELLS' SYNDROME)
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- Shodo Makoto
- Department of Dermatology. Toyama Rosai Hospital
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- Mizuhashi Keiichi
- Department of Internal Medicine. Toyama Rosai Hospital
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- Kimura Tetsunori
- Sapporo Institute for Dermatopathology
Bibliographic Information
- Other Title
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- Eosinophilic Cellulitisの1例
- 症例報告 Eosinophilic Cellulitisの1例
- ショウレイ ホウコク Eosinophilic Cellulitis ノ 1レイ
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Abstract
A 67-year-old man sustained a minor injury on the right hand after touching a potted plant. Several days later, he noted erythema and marked swelling on the right hand and forearm. The same lesions developed on the left hand and forearm. He also had pruritic erythema on the neck, trunk, and thighs. The initial clinical diagnosis was bacterial cellulitis and contact dermatitis. However, oral antibiotic and topical steroid therapy were not effective. Laboratory investigations revealed peripheral blood eosinophilia, elevated serum IgE Ievel, and positive antinuclear antibody. Histopathological examination of a skin biopsy specimen showed an excessive infiltration of eosinophils and flame figures in the dermis. We diagnosed this case as eosinophilic cellulitis (Wells' syndrome) . The skin lesions responded rapidly to the systemic oral steroid therapy. There has been no recurrence of eruption in I year of follow-up. The condition of the disease was correlated to peripheral blood eosinophil counts, and serum eosinophil cationic protein levels. However, serum interleukin-5 Ievels were within normal limits.
Journal
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- Japanese Journal of Allergology
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Japanese Journal of Allergology 53 (10), 1079-1083, 2004
Japanese Society of Allergology
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Details 詳細情報について
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- CRID
- 1390282679962038272
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- NII Article ID
- 110002435799
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- NII Book ID
- AN00012583
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- ISSN
- 13477935
- 00214884
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- NDL BIB ID
- 026062702
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed