Effects of Volume Loading on Pulmonary Venous Flow and its Relation to Left Atrial Functions
-
- Hondo Tatsuya
- First Department of Internal Medicine, Hiroshima University School of Medicine
-
- Okamoto Mitsunori
- First Department of Internal Medicine, Hiroshima University School of Medicine
-
- Kawagoe Takuji
- First Department of Internal Medicine, Hiroshima University School of Medicine
-
- Yamane Tetsuya
- First Department of Internal Medicine, Hiroshima University School of Medicine
-
- Karakawa Shinji
- First Department of Internal Medicine, Hiroshima University School of Medicine
-
- Yamagata Togo
- First Department of Internal Medicine, Hiroshima University School of Medicine
-
- Matsuura Hideo
- First Department of Internal Medicine, Hiroshima University School of Medicine
-
- Kajiyama Goro
- First Department of Internal Medicine, Hiroshima University School of Medicine
Search this article
Abstract
Although pulmonary venous (PV) flow is closely related to left atrial (LA) pressure dynamics, few investigators have discussed it in relation to LA functions, ie, reservoir, conduit, and booster pump functions. We examined changes in PV flow rate, LA dimension, and left ventricular filling volume in 11 dogs, and assessed the effects of multistaged volume loading on PV flow and LA functions. Systolic PV flow rate (S) increased significantly and reached a plateau, reflecting a limited LA reservoir function. Diastolic PV flow rate (D) increased significantly with an increase in LA pressure. S/D ratio increased non-significantly from 0.87±0.07 before volume loading to 0.96±0.08 until S reached a plateau and then decreased to 0.76±0.08 (p<0.05) because of a significant increase in D without an increase in S at the higher stages of volume loading. During atrial contraction, increases in LA active shortening and left ventricular filling volume were limited, indicating a limited LA forward ejection. The difference between PV flow rate just before and at the end of atrial contraction increased and correlated positively with left ventricular end-diastolic pressure (r=0.57, p<0.01). PV flow varies according to the degree of volume loading and reflects LA functions, which exhibit limited increases in response to volume loading. (Jpn Circ J 1997; 61: 1015 - 1020)
Journal
-
- Japanese Circulation Journal
-
Japanese Circulation Journal 61 (12), 1015-1020, 1997
The Japanese Circulation Society
- Tweet
Details 詳細情報について
-
- CRID
- 1390001206428243456
-
- NII Article ID
- 110002564469
-
- NII Book ID
- AA00690731
-
- COI
- 1:STN:280:DyaK1c%2FnsVentA%3D%3D
-
- ISSN
- 13474839
- 00471828
-
- PubMed
- 9412866
-
- Text Lang
- en
-
- Data Source
-
- JaLC
- Crossref
- PubMed
- CiNii Articles
-
- Abstract License Flag
- Disallowed