Transcatheter Neodymium-Yttrium-Aluminum-Garnet Laser Coagulation of Canine Ventricle Using a Balloon-Tipped Cardioscope

• HIRAO Kenzo

  First Department of Internal Medicine, School of Medicine, Tokyo Medical and Dental University

• YAMAMOTO Naohito

  First Department of Internal Medicine, School of Medicine, Tokyo Medical and Dental University

• TOSHIDA Nobuo

  First Department of Internal Medicine, School of Medicine, Tokyo Medical and Dental University

• NAWATA Hiroko

  First Department of Internal Medicine, School of Medicine, Tokyo Medical and Dental University

• ISHIHARA Naoko

  First Department of Internal Medicine, School of Medicine, Tokyo Medical and Dental University

• SUZUKI Fumio

  First Department of Internal Medicine, School of Medicine, Tokyo Medical and Dental University

• MIYASAKA Nobuyuki

  First Department of Internal Medicine,School of Medicine,Tokyo Medical and Dental University

• HIEJIMA Kazumasa

  Department of Allied Health Sciences,School of Medicine,Tokyo Medical and Dental University

• TANAKA Michio

  Department of Pathology, Tokyo Metropolitan Hiroo General Hospital

抄録

The feasibility of transcatheter laser ablation of the canine left ventricle (LV) was tested using a newly developed cardioscope. In 17 anesthetized dogs, a combined laser-endoscope catheter, consisting of an endoscope encased in a 7-French flexible catheter with an inflatable and transparent balloon at the distal end, was introduced into the LV via the carotid artery. A 1064-nm neodymium-yttrium-aluminum-garnet (Nd:YAG) laser was delivered by laser optic fiber, which was introduced through the transport channel and positioned inside the saline-filled balloon. In 16 of 17 dogs, the endocardial surface of the LV was clearly observed. Laser energy totaling 500-5,000 J was applied sequentially in 13 dogs and laser irradiation was completed in all but 2 of the dogs. The excised hearts revealed well-demarcated oval-shaped lesions 2.5-9.5 mm deep in 7 of 11 dogs. Histologic sections revealed coagulation necrosis surrounded by a rim of contraction band necrosis. Thus, transballoon laser photocoagulation of the beating LV is feasible. The newly combined laser-endoscope catheter, which is still in its preliminary stages and needs to be improved to increase the success rate of photocoagulation, appears to be a promising alternative modality for catheter ablative therapy for ventricular tachycardia.

収録刊行物

• Japanese circulation journal

  Japanese circulation journal 61 (8), 695-703, 1997-07-20

  社団法人日本循環器学会

キーワード

• Laser coagulation of ventricular myocardium
• Angioscopy
• Catheter ablation
• Ventricular tachycardia

詳細情報

• CRID: 1573105977033303680
• NII論文ID: 110002564848
• NII書誌ID: AA00690731
• ISSN: 00471828
• Web Site: https://search.jamas.or.jp/link/ui/1997249482
• 本文言語コード: en
• データソース種別:
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