Effects of glucose-insulin-potassium infusion on myocardial infarction and myocardial blood flow following experimental coronary artery occlusion.

• KAMBARA HIROFUMI

• YOSHIDA AKIRA

• KAWASHITA KENJI

• KAWAI CHUICHI

書誌事項

タイトル別名

• Effects of Glucose Insulin Potassium In

抄録

To determine the therapeutic effects of glucose-insulin-potassium (GIK) solution, 5 control dogs and 5 GIK-treated dogs were investigated 24 hours after coronary artery occlusion by use of myocardial creatine phosphokinase (CK) activity and myocardial thallium-201 uptake. There was no significant difference in myocardial blood flow estimated by thallium-201 uptake between the control and the GIK group, but myocardial CK activity in the ischemic zone of GIK-treated animals was significantly higher than that of the control group. This suggests that administration of GIK solution is effective in protecting myocardial tissue in the central ischemic area and that this protecting action of GIK seems to be independent of myocardial blood flow.

収録刊行物

• JAPANESE CIRCULATION JOURNAL

  JAPANESE CIRCULATION JOURNAL 45 (10), 1158-1163, 1981

  社団法人 日本循環器学会

キーワード

• Glucose-insulin-potassium (GIK)
• Myocardial blood flow
• Thallium-201
• Myocardial infarction

詳細情報

• CRID: 1390282681408950016
• NII論文ID: 130003546794
• NII論文ID: 110002582684
• NII書誌ID: AA00690731
• DOI: 10.1253/jcj.45.1158
• COI: 1:CAS:528:DyaL38XotVeisQ%3D%3D
• ISSN: 13474839
• ISSN: 00471828
• NDL書誌ID: 2360929
• PubMed: 7029026
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I2360929
• Web Site: http://www.jstage.jst.go.jp/article/circj1960/45/10/45_10_1158/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可