Intravascular ultrasound imaging in human peripheral and coronary arteries in vivo.

• MORIUCHI M.

  Second Department of Internal Medicine Nihon University School of Medicine

• SAITO SATOSHI

  Second Department of Internal Medicine Nihon University School of Medicine

• HONYE JUNKO

  Second Department of Internal Medicine Nihon University School of Medicine

• TAMURA YASUO

  Second Department of Internal Medicine Nihon University School of Medicine

• HIBIYA KAZUHIRA

  Second Department of Internal Medicine Nihon University School of Medicine

• MORIUCHI RIKA

  Second Department of Internal Medicine Nihon University School of Medicine

• KAMATA TOMOHIKO

  Second Department of Internal Medicine Nihon University School of Medicine

• TSUJI MASAZUMI

  Second Department of Internal Medicine Nihon University School of Medicine

• MIZUMURA TSUNEO

  Second Department of Internal Medicine Nihon University School of Medicine

• DON MAHON

  Division of Cardiology University of California, Irvine

• J0HN A MALLERY

  Division of Cardiology University of California, Irvine

• J0NATHAN M TOBIS

  Division of Cardiology University of California, Irvine

抄録

To detemine the feasibility of intravascular ultrasound imaging in vivo, a miniaturized high frequency transducer catheter was introduced into human peripheral (n=10) and coronary (n=4) arteries. Cross-sectional ultrasound images were obtained from iliofemoral arteries in 10 patients using a 20 MHZ transducer catheter (1.2 mm in diameter) and from coronary arteries in 4 patients using a 30 MHZ transducer catheter 5 French size (Fr) following successful coronary angioplasty. Ultrasound images obtained from peripheral arteries showed a three-layered appearance (echo-reflective intima, echo-lucent media and echo-reflective adventitia) in the normal arteries. In diseased arteries, the location, amount and extent of atheromatous plaque were clearly documented. The arterial diameters measured by ultrasound closely correlated with the measurements by angiography (r=0.91) in the peripheral arteries. Coronary angiograms obtained following balloon angioplasty revealed smooth edges at the dilatation sites without significant narrowing in all patients. However, a significant amount of residual atheromatous plaque was clearly observed on the ultrasound images at the previously dilated sites. Coronary dissection, which was identified as an echo-lucent area behind the plaque, was noted in 2 patients. Ultrasound images also revealed the presence of calcium in the plaque which was unrecognized on the angiograms in 3 patients. In addition, direct measurement of the lumen cross-sectional area was possible on the ultrasound images. These results indicate that (1) the clinical use of intravascular ultrasound imaging catheters is feasible in human peripheral and coronary arteries in vivo, (2) both quantitative and qualitative assessments of atheromatous plaque are possible, and (3) this device will be useful for determining the quantitative and morphologic changes following coronary angioplasty.

収録刊行物

• Jpn Circ J

  Jpn Circ J 56 578-585, 1992

  社団法人日本循環器学会

キーワード

• Intravascular ultrasound
• Atherosclerosis
• Coronary angioplasty

詳細情報

• CRID: 1573668926924284160
• NII論文ID: 110002587519
• NII書誌ID: AA00690731
• ISSN: 00471828
• Web Site: https://search.jamas.or.jp/link/ui/1994082036
• 本文言語コード: en
• データソース種別:
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