Cerebral blood flow in asymptomatic individuals : relationship with cerebrovascular risk factors and magnetic resonance imaging signal abnormalities

被引用文献1件
  • ISAKA Y
    Department of Nuclear Medicine Osaka National Hospital Department of Neurology Osaka National Hospital
  • IIJI OSAMU
    Department of Neurology Osaka National Hospital
  • ASHIDA KEIICHI
    Department of Neurology Osaka National Hospital
  • IMAIZUMI MASATOSHI
    Department of Neurology Osaka National Hospital

この論文をさがす

抄録

We studied the relationship between cortical grey matter flow (CBF) and age, cerebrovascular risk factors and the severity of subcortical hypersignals (HS, hyperintensity score in MRI) in 47 asymptomatic subjects with cerebrovascular risk factors. Multiple regression analysis revealed that HS was most strongly related to CBF, and that hematocrit, age and evidence of ischemic change detected in the electrocardiogram also appeared to be independent determinants of CBF. Both the severity and location of hypersignals were correlated with CBF. The most significant negative correlation observed was that between CBF and HS in the basal ganglia-thalamic region, where the degree of signal abnormality was modest. Decreased CBF in asymptomatic subjects with cerebrovascular risk factors may be related to (1) microcirculatory disturbance associated with elevated hematocrit and an increase in the number of risk factors, and (2) functional suppression of cerebral cortex due to the neuronal disconnection associated with subcortical lesions. In addition, impaired cerebral circulation may be related to MRI signal abnormalities.

収録刊行物

  • Jpn Circ J

    Jpn Circ J 57 283-290, 1993

    社団法人日本循環器学会

被引用文献 (1)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ