Effect of Graded Coronary Constriction on Regional Oxygen and Carbon Dioxide Tensions in Outer and Inner Layers of the Canine Myocardium
書誌事項
- タイトル別名
-
- EFFECTS OF GRADED CORONARY CONSTRICTION ON REGIONAL OXYGEN AND CARBON DIOXIDE TENSIONS IN OUTER AND INNER LAYERS OF THE CANINE MYOCARDIUM
- Effect of Graded Coronary Constriction
この論文をさがす
抄録
This study was undertaken to investigate the effects of graded coronary constriction on regional gas tensions of the myocardium. In 12 open chest dogs, tissue carbon dioxide (PtCO2) and oxygen (PtO2) tensions were measured simultaneously in outer and inner layers of the myocardium using a mass spectrometer. In normal condition, higher PtO2 and lower PtCO2 were observed in outer layer than in inner layer. With application of coronary constriction, increase in PtCO2 and decrease in PtO2 were observed in both layers of the myocardium, but the response to the ischemic stimuli by applying coronary constriction in inner layer was different from that in outer layer. Severe coronary constriction, more than 90% in its diameter, was necessary to produce significant changes in both gas tensions in both layers of the myocardium. Decrease in PtO2 was found in the condition of less severe coronary constriction and to be greater in inner layer than in outer layer of the myocardium. In terms of the changes in PtCO2, inner layer was also more susceptible to the ischemic stimuli than outer layer. The greater and earlier elevation of PtCO2 in inner layer than in outer layer is regarded as one of the possible mechanisms of the reduction of myocardial contraction in the early stage of myocardial ischemia.
収録刊行物
-
- JAPANESE CIRCULATION JOURNAL
-
JAPANESE CIRCULATION JOURNAL 42 (6), 701-709, 1978
社団法人 日本循環器学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001206432589440
-
- NII論文ID
- 130003546566
- 110002614150
-
- NII書誌ID
- AN00191970
-
- COI
- 1:STN:280:DyaE1M%2FltVylsg%3D%3D
-
- ISSN
- 13474839
- 00471828
-
- NDL書誌ID
- 1949030
-
- PubMed
- 713021
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可