Fluorescein Studies of Hypertensive Retinopathy

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A more accurate observation of retina and vessels was made by the fluorescence angiograms than the ones made by ophthalmoscope and routine color photography. The method proved to be the most effective in detecting the soft exudates caused by increase in permeability and damage of arteriole walls. The soft exudates revealed by this method occur in many hypertensive patients with abnormal ECG. No conspicuous difference was observed in the measurement of the caliber of artery and vein of a normal person either by color or fluorescein photography. The differences however, become greater as copper wire artery and silver wire artery. Observation was also made on fluorescein photographs at the time of blood pressure raised by means of cold pressure and intravenous injection of methoxamine and also at the time of blood pressure lowered by means of sodium nitrite treatment.

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