Cloning and Selective Toxicant-induced Expression of BMR1 and BMR3,Novel ABC Transporter Genes in Botrytis cinerea :

  • MAKIZUMI,Yoshiyuki
    Department of Agricultural and Environmental Biology,The University of Tokyo
  • TAKEDA,Shin-ichi
    Department of Agricultural and Environmental Biology,The University of Tokyo
  • MATSUZAKI,Yuichi
    Department of Agricultural and Environmental Biology,The University of Tokyo
  • NAKAUNE,Ryoji
    National Institute of Fruit Tree Science
  • HAMAMOTO,Hiroshi
    Department of Agricultural and Environmental Biology,The University of Tokyo:Bio-oriented Technology Research Advancement Institution (BRAIN):(Present address)Plant Science Center,RIKEN
  • AKATSU,Katsumi
    Faculty of Agriculture,Ibaraki University
  • HIBI,Tadaaki
    Department of Agricultural and Environmental Biology,The University of Tokyo

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Two genes, BMR1 and BMR3, encoding new members of the ABC superfamily in Botrytis cinerea, were cloned and characterized. The topologies of the encoded proteins, BMR1 and BMR3, were both (NBF-TMD_6)_2, similar to most of the toxicant-efflux ABC transporters. These genes had different induced expression patterns after treatment with various toxicants, suggesting they may have different roles in toxicant-resistance. (Received September 24, 2002 ; Accepted December 2, 2002)

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