Monitoring the Progression of the Atrial Electrical Remodeling in Patients With Paroxysmal Atrial Fibrillation. Analysis of the f-f Interval During Ambulatory ECG Monitoring.

• Niwano Shinichi

  Department of Internal Medicine, Kitasato University School of Medicine

• Wakisaka Yuko

  Department of Internal Medicine, Kitasato University School of Medicine

• Kojima Jisho

  Department of Internal Medicine, Kitasato University School of Medicine

• Yumoto Yoshihiro

  Department of Internal Medicine, Kitasato University School of Medicine

• Inuo Kimiatsu

  Department of Internal Medicine, Kitasato University School of Medicine

• Hara Hideyuki

  Department of Internal Medicine, Kitasato University School of Medicine

• Saito Junko

  Department of Internal Medicine, Kitasato University School of Medicine

• Niwano Hiroe

  Department of Internal Medicine, Kitasato University School of Medicine

• Izumi Tohru

  Department of Internal Medicine, Kitasato University School of Medicine

書誌事項

タイトル別名

• Analysis of the f-f Interval During Ambulatory ECG Monitoring

抄録

It is important to clarify how electrical remodeling develops in clinical cases of paroxysmal atrial fibrillation (PAF), because it has been suggested that this electrophysiological phenomenon promotes an increase in the frequency of PAF. In the present study, the f-f interval during PAF was analyzed from the ambulatory ECG recordings of 21 patients with PAF (total PAF duration >2/24 h with normal atrial size) to monitor the atrial electrophysiological changes. The patients were clinically followed-up for 6 months without any antiarrhythmic drugs. Before and after the follow-up period 24-h Holter monitoring was carried out and the duration of both the PAF and the f-f intervals during the PAF episode were evaluated. In selected cases, the atrial effective refractory period (ERP) was evaluated in an electrophysiologic study before and after the follow-up period. The total PAF duration was prolonged from 187±50 to 223±79 min (p=0.034) and the f-f interval was shortened from 0.14±0.03 to 0.12±0.02 ms (p=0.003). There was an inverse relationship between the changes in total PAF duration and f-f interval (p=0.027). The ERP was shortened from 214±15 to 194±5 ms (n=5, p=0.025) and there was a direct correlation between the changes in ERP and f-f interval (p=0.048). In clinical cases, the prolongation of the PAF was related to the shortening of the f-f interval during the PAF episodes and to the shortening of the atrial ERP. Electrical remodeling plays a role in promoting the development of the atrial fibrillation in patients with PAF. (Circ J 2003; 67: 133 - 138)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 67 (2), 133-138, 2003

  一般社団法人 日本循環器学会

キーワード

• Atrial fibrillation
• Atrial refractoriness
• Electrical remodeling
• Holter monitoring

詳細情報

• CRID: 1390001205103605376
• NII論文ID: 110002666265
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.67.133
• COI: 1:STN:280:DC%2BD3s%2FjvFersw%3D%3D
• ISSN: 13474820
• ISSN: 13469843
• ISSN: http://id.crossref.org/issn/13469843
• PubMed: 12547995
• Web Site: http://www.jstage.jst.go.jp/article/circj/67/2/67_2_133/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2003166620
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可