Antitumor Active Polysaccharides from the Chinese Mushroom<i>Songshan Lingzhi</i>, the Fruiting Body of<i>Ganoderma tsugae</i>

• Wang Guanying

• Zhang Jie

• Mizuno Takashi

• Zhuang Cun

• Ito Hitoshi

• Mayuzumi Humimaru

• Okamoto Hidehumi

• Li Jingxuan

書誌事項

タイトル別名

• Antitumor Active Polysaccharides from the Chinese Mushroom Songshan Lingzhi, the Fruiting Body of Ganoderma tsugae.
• Antitumor active polysaccharides from the Chinese mushroom Songshan Lingzhi, the fruitng body of Ganoderma tsugae

抄録

A systematic method of extraction, fractionation, and purification of polysaccharides from Songshan Lingzhi (Ganoderma tsugae) with antitumor activity was established. Seven glycans with strong antitumor activities were obtained from 14 water-soluble, and 15 water-insoluble fractions: FI_o-a, FA-1, FII-1, FIII-2, and FIII-2-a, -b, and -c. FI_o-a and FA-1 were protein-containing glucogalactans associated with mannose and fucose. FII-1 was a (1→3)-β-D-glucan having a lower protein content. The water-insoluble fractions FIII-2-a, -b, and -c were extracted with alkali, and were found to be protein-containing (1→3)-β-D-glucans showing the strongest activity. Chemical properties and structure of each antitumor polysaccharide were compared with three fungi of the Ganoderma family, Kofukitake (G. applanatum), Mannentake (G. lucidum), and Songshan Lingzhi (G. tsugae).

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 57 (6), 894-900, 1993

  公益社団法人 日本農芸化学会

キーワード

• Organic Chemistry
• Molecular Biology
• Applied Microbiology and Biotechnology
• General Medicine
• Biochemistry
• Analytical Chemistry
• Biotechnology

詳細情報

• CRID: 1390001206470493312
• NII論文ID: 110002676375
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.57.894
• COI: 1:CAS:528:DyaK3sXlsFGktL0%3D
• ISSN: 13476947
• ISSN: 09168451
• ISSN: http://id.crossref.org/issn/09168451
• PubMed: 7763875
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.57.894
• Web Site: https://search.jamas.or.jp/link/ui/1995082331
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可