Amphotericin B Resistance Assay for the Detection of Cholesterol Biosynthesis Inhibitors.

• Maeba Hideo

• Narihata Hiroyuki

• Kobayashi Fujio

Abstract

Three different types of cholesterol biosynthesis inhibitors, lovastatin, ketoconazole, and 25-hydroxycholesterol, showed their respective resistance against amphotericin B (AmB) cytotoxicity in Chinese hamster ovary (CHO)-K1 cells. The negative correlation between the acquisition of AmB resistance and the decrease of cellular cholesterol content by the inhibitor was confirmed.

Journal

• Bioscience, Biotechnology, and Biochemistry

  Bioscience, Biotechnology, and Biochemistry 58 (7), 1321-1323, 1994

  Japan Society for Bioscience, Biotechnology, and Agrochemistry

Keywords

• Organic Chemistry
• Molecular Biology
• Applied Microbiology and Biotechnology
• General Medicine
• Biochemistry
• Analytical Chemistry
• Biotechnology

Details

• CRID: 1390282681452850816
• NII Article ID: 110002677082
• NII Book ID: AA10824164
• DOI: 10.1271/bbb.58.1321
• ISSN: 13476947
• ISSN: 09168451
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.58.1321
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed