A Close Correlation between Improvement of Organic Solvent Tolerance Levels and Alteration of Resistance toward Low Levels of Multiple Antibiotics in<i>Escherichia coli</i>

• Aono Rikizo

• Kobayashi Masato

• Nakajima Harushi

• Kobayashi Hideki

書誌事項

タイトル別名

• A Close Correlation between Improvement of Organic Solvent Tolerance Levels and Alteration of Resistance toward Low Levels of Multiple Antibiotics in Escherichia coli.

抄録

We have isolated cyclohexane-tolerant mutants from Escherichia coli strain JA300, which is cyclohexane-sensitive and n-hexane-tolerant. These mutants were resistant to low levels of ampicillin, chloramphenicol, nalidixic acid, and tetracycline, and were sensitive to a low level of kanamycin. Spontaneous clones resistant to low levels of the antibiotics, isolated from JA300, showed altered levels of organic solvent tolerance. The clones resistant to ampicillin and chloramphenicol had cyclohexane tolerance. Some of the resistant clones had cyclohexane and n-pentane tolerances. On the other hand, some kanamycin resistant clones became sensitive to n-hexane. Therefore, mechanisms to improve tolerance levels toward organic solvents are closely correlated with some antibiotic resistant system to low levels of antibiotics.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 59 (2), 213-218, 1995

  公益社団法人 日本農芸化学会

キーワード

• Organic Chemistry
• Molecular Biology
• Applied Microbiology and Biotechnology
• General Medicine
• Biochemistry
• Analytical Chemistry
• Biotechnology

詳細情報

• CRID: 1390282681450838144
• NII論文ID: 110002677412
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.59.213
• COI: 1:CAS:528:DyaK2MXktFGjtb0%3D
• ISSN: 13476947
• ISSN: 09168451
• PubMed: 7766020
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.59.213
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可