Inhibitory Effects of Caffeic Acid Ethyl Ester on H₂O₂-induced Cytotoxicity and DNA Single-strand Breaks in Chinese Hamster V79 Cells

• NAKAYAMA Tsutomu

• YAMADA Munetaka

• OSAWA Toshihiko

• KAWAKISHI Shunro

書誌事項

タイトル別名

• Inhibitory Effects of Caffeic Acid Ethyl Ester on H2O2-induced Cytotoxicity and DNA Single-strand Breaks in Chinese Hamster V79 Cells.

抄録

Cytotoxicity and DNA single-strand breaks caused by H₂O₂were assessed by a colony formation assay and a DNA precipitation assay, respectively, with Chinese hamster V79 cells. In both assays, caffeic acid ethyl ester showed protective effects. The structure-activity relationship showed that the o-dihydroxy structure of caffeic acid ethyl ester was essential for the protective effects.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 60 (2), 316-318, 1996

  公益社団法人 日本農芸化学会

キーワード

• hydrogen peroxide
• cultured cell
• DNA strand break
• caffeic acid ethyl ester
• polyphenol

詳細情報

• CRID: 1390001206474045952
• NII論文ID: 110002677994
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.60.316
• COI: 1:CAS:528:DyaK28XhtlKnu7w%3D
• ISSN: 13476947
• ISSN: 09168451
• ISSN: http://id.crossref.org/issn/09168451
• PubMed: 9063980
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.60.316
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可