Structures and activity of cellulase inhibitors synthesized enzymatically from cellooligosaccharides and deoxynojirimycin

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  • Structures and Activity of Cellulase Inhibitors Enzymatically Synthesized from Cellooligosaccharides and 1-Deoxynojirimycin.

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Cellulase inhibitors were synthesized from cellooligosaccharides and 1-deoxynojirimycin (DNJ) by transglycosylation, using a commercial cellulase. The structures of these cellulase inhibitors were proved to be 4-O-β-cellobiosyl-DNJ, 4-O-β-D-glucopyranosyl-DNJ and 6-O-β-cellobiosyl-DNJ by the results of 13C- and 1H-NMR analyses. The inhibitory activity of each inhibitor was investigated against several carboxymethylcellulases.

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