Preparation of Oligosaccharide Units Library and Its Utilization.
書誌事項
- タイトル別名
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- Preparation of Oligosaccharide Units Li
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There is high current interest in developing synthetic routes to oligosaccharides involved in glycoconjugates. Significant attention has been focused on the application of glycosidase-catalyzed transglycosylation for practical synthesis of oligosaccharides. The enzymatic synthesis has become more practical by the use of several glycosidases available in sufficient quantities. This review desbribes convenient syntheses of di- and trisaccharide units' which are related to molecular recognition, by using regioselective transgalactosylation, trans-N-acetylglucosaminylation, transfucosylation, and transmannosylation. The regioselectivity could be controlled to some extent by using the following techniques: (1) varying enzymed, (2) organic co-solvent system, (3) the configuration of the existing glycosidic linkage of the acceptor and (4) inclusion complex of acceptor glycoside with cyclodextrin. Furthermore, glycopolymers carrying a series of disaccharides containing β-D-galactosyl resideues were synthesized and used as a model in oligosaccharide-lectin interaction analyses. These water-soluble glycopolymers were shown to be useful as probes of carbohydrate recognition.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 61 (7), 1059-1066, 1997
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390282681453226496
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- NII論文ID
- 110002678647
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- NII書誌ID
- AA10824164
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- COI
- 1:CAS:528:DyaK2sXltVagur4%3D
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- ISSN
- 13476947
- 09168451
- http://id.crossref.org/issn/09168451
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- NDL書誌ID
- 4270690
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- PubMed
- 9255967
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可