Morphological Changes in Insect BM-N4 Cells Induced by Nocardamine.

  • MATSUBARA Ken
    Department of Applied Biological Chemistry, The University of Tokyo
  • SAKUDA Shohei
    Department of Applied Biological Chemistry, The University of Tokyo
  • KONDO Tatsuhiko
    Department of Applied Biological Chemistry, The University of Tokyo
  • TANAKA Minoru
    Department of Applied Biological Chemistry, The University of Tokyo
  • NISHIMURA Toshio
    Department of Science and Technology, Teikyo University
  • SUZUKI Akinori
    Department of Applied Biological Chemistry, The University of Tokyo

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  Nocardamine, a kind of siderophore, was isolated as an inducer of morphological changes in the insect cells, BM-N4. It changed the morphology of the cells from round to an unusual spindle shape. This activity of nocardamine was inhibited by adding the ferric ion.<br>

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