Effects of Tea Infusions of Various Varieties or Different Manufacturing Types on Inhibition of Mouse Mast Cell Activation.

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  • MAEDA-YAMAMOTO Mari
    National Research Institute of Vegetables, Ornamental Plants and Tea, Ministry of Agriculture, Forestry and Fisheries
  • KAWAHARA Hiroharu
    Bio-oriented Technology Research Advancement Institution
  • MATSUDA Nahomi
    National Research Institute of Vegetables, Ornamental Plants and Tea, Ministry of Agriculture, Forestry and Fisheries
  • NESUMI Kouji
    National Research Institute of Vegetables, Ornamental Plants and Tea, Ministry of Agriculture, Forestry and Fisheries
  • SANO Mitsuaki
    University of Shizuoka
  • TSUJI Kenkou
    National Research Institute of Vegetables, Ornamental Plants and Tea, Ministry of Agriculture, Forestry and Fisheries
  • KAWAKAMI Yuko
    La Jolla Institute for Allergy and Immunology
  • KAWAKAMI Toshiaki
    La Jolla Institute for Allergy and Immunology

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  We investigated effects of various tea infusions on mast cell activation using mouse mast cells. Among various tea extracts, infusions from cultivar ‘Benihomare’ and Taiwan lineage strongly inhibited histamine release after FcεRI cross-linking. Among three types of tea (from cultivar ‘Benihomare’), extract from oolong tea or black tea inhibited histamine release more strongly than green tea extract. Furthermore, ‘Benihomare’ oolong tea extract suppressed tyrosine phosphorylation of cellular proteins after FcεRI cross-linking, but polyvinyl polypyrrolidone treatment of the extract to remove phenolic compounds, weakened the suppressive effect.<br>

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