Synthesis of a Novel Phosphate Ester of a Vitamin E Derivative and Its Antioxidative Activity.

• MIYAMOTO Sayuri

  National Food Research Institute, The Ministry of Agriculture, Forestry and Fisheries

• KOGA Takuro

  Noda Institute for Scientific Research

• TERAO Junji

  Department of Nutrition, School of Medicine, The University of Tokushima

抄録

  A novel phosphate ester containing a chromanol structure was synthesized from 1,2-diacyl-sn-glycero-3- phospho-2′-hydroxyethyl-2′,5′,7′,8′-tetramethyl-6′-hydro-xychroman (PCh) by hydrolysis catalyzed by phospholipase C from Bacillus cereus. The structure of the product was found by spectral analyses to be 2-(2′,5′,7′,8′-tetramethyl-6′-hydroxychromanyl)ethylphosphate (Ch-P). Ch-P was highly soluble in the aqueous phase at neutral pH values and exerted higher antioxidative activity than α-tocopherol and PCh in the Fe(III)/ascorbic acid-catalyzed peroxidation of a fish oil emulsion and the autoxidation of a rat brain homogenate.<br>

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 62 (12), 2463-2466, 1998

  公益社団法人 日本農芸化学会

キーワード

• vitamin E
• phospholipase C
• antioxidant activity
• tocopherol
• chromanol

詳細情報

• CRID: 1390001206473777920
• NII論文ID: 110002679160
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.62.2463
• COI: 1:CAS:528:DyaK1MXltV2gtA%3D%3D
• ISSN: 13476947
• ISSN: 09168451
• NDL書誌ID: 1524316
• PubMed: 9972276
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I1524316
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.62.2463
• Web Site: https://search.jamas.or.jp/link/ui/1999135593
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可