Dehydroascorbic Acid Reduction in Several Tissues and Cultured Hepatocytes of the Chicken.

• SASAKI Keisuke

  Department of Animal Products, National institute of Livestock and Grassland Science

• KITAGUCHI Yasunari

  Laboratory of Animal Nutrition, Ibaraki University

• KOGA Kengo

  Laboratory of Animal Nutrition, Ibaraki University

• NARITA Rei

  Laboratory of Animal Nutrition, Ibaraki University

• FUKUDA Tatsuki

  Laboratory of Animal Nutrition, Ibaraki University

• AOYAGI Yosuke

  Laboratory of Animal Nutrition, Ibaraki University

抄録

Dehydroascorbic acid, the oxidized form of ascorbic acid, is rapidly reduced to ascorbate in living organs (ascorbate recycling). We examined the GSH-dependent dehydroascorbate reductase activity in several tissues of the chicken. The activity was highest in the liver, and second highest in the brain. The activity was localized in the cytosol fraction of the liver. We subsequently examined the dehydroascorbate reduction in separated chiken hepatocytes. The cellular ascorbate concentration was elevated in dehydroascorbate-treated cells. It is thought that hepatocytes incorporated external dehydroascorbate and converted it into ascorbate. These findings suggest that the liver plays an important role in ascorbate recycling by the chicken.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 65 (10), 2288-2290, 2001

  公益社団法人 日本農芸化学会

キーワード

• dehydroascorbic acid
• chicken
• GSH-dependent dehydroascorbic acid reductase
• hepatocytes

詳細情報

• CRID: 1390282681453355136
• NII論文ID: 110002693274
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.65.2288
• COI: 1:CAS:528:DC%2BD3MXotFanu7c%3D
• ISSN: 13476947
• ISSN: 09168451
• NDL書誌ID: 5969396
• PubMed: 11758923
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I5969396
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.65.2288
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可