Quantitative assessment of regional myocardial flow reserve using tc-99m-sestamibi imaging
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- Tsukamoto Takahiro
- Departments of Cardiovascular Medicine, Hokkaido University
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- Ito Yoshinori
- Departments of Cardiovascular Medicine, Hokkaido University
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- Noriyasu Kazuyuki
- Departments of Cardiovascular Medicine, Hokkaido University
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- Morita Koichi
- Nuclear Medicine, Graduate School of Medicine, Hokkaido University
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- Katoh Chietsugu
- Nuclear Medicine, Graduate School of Medicine, Hokkaido University
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- Okamoto Hiroshi
- Departments of Cardiovascular Medicine, Hokkaido University
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- Tamaki Nagara
- Nuclear Medicine, Graduate School of Medicine, Hokkaido University
書誌事項
- タイトル別名
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- Quantitative Assessment of Regional Myocardial Flow Reserve Using Tc-99m-Sestamibi Imaging-Comparison With Results of O-15 Water PET-
- Comparison With Results of O-15 Water PET
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Background The aims of this study were to develop a method for quantitative estimation of the myocardial blood flow index (MBFI) and myocardial flow reserve (MFR) of the whole left ventricle using 99mtechnetium (Tc-99m)-sestamibi imaging. Methods and Results Twenty-two patients with suspected coronary artery disease and 7 controls underwent both Tc-99m-sestamibi imaging and O-15 water positron emission tomography (PET). The global MBFI was calculated on the basis of the microsphere model from the ratio of the myocardial count to the area under the time - activity curve on the aortic arch. The regional MBFI was calculated from the relative distributions of Tc-99m-sestamibi uptake values. The regional MBFI and MFR (Tc-MFR) obtained using single-photon emission computed tomography were compared with the myocardial blood flow (MBF) and MFR (PET-MFR) obtained using PET as the gold standard. Regional MBFI significantly correlated with the MBF obtained using PET. Regional Tc-MFR also correlated with the regional PET-MFR, with some underestimation. Conclusion These results indicate that regional MBF and MFR may be estimated by dynamic Tc-99m-sestamibi imaging and can be used for the early detection and estimation of the functional severity of coronary lesions without the need for a PET camera. (Circ J 2005; 69: 188 - 193)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 69 (2), 188-193, 2005
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390001205102498432
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- NII論文ID
- 110002696069
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
- http://id.crossref.org/issn/13469843
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- PubMed
- 15671611
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 使用不可