Simultaneous Multiple Breast Adenomata and Tubular Adenoma in Identical Twins

DOI 5 Citations
  • MATSUDA Minoru
    Second Department of Surgery, Kyorin University School of Medicine
  • NABEYA Kinichi
    Second Department of Surgery, Kyorin University School of Medicine
  • HANAOKA Tateo
    Second Department of Surgery, Kyorin University School of Medicine
  • ARAI Yuji
    Second Department of Surgery, Kyorin University School of Medicine
  • FUKUSHIMA Hisaki
    Second Department of Surgery, Kyorin University School of Medicine
  • KOBAYASHI Yoshihiro
    Second Department of Surgery, Kyorin University School of Medicine
  • FUKUZUMI Naoyoshi
    Department of Surgical Pathology, Kyorin University School of Medicine

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  • 一卵性双生児にみられた同時性右乳腺線維腺腫および管状腺腫

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Abstract

Identical twins, 23 years in age, were seen to our clinic with chief complaints of multiple tumor nodes palpable in the right breast. When the older and younger sister were examined in 1984, three tumor nodes were found in the right breast with a maximal diameter of 5.2cm and 5.5cm for each case. Under the diagnosis of fibroadenomata, tumor resectomies were done when the pathological diagnosis of fibroadenoma and/or fibroadenoma with tubular adenoma were given. Borderline malignancy was identified in the tumor nodes of the older sister. The sisters were confirmed as the identical twins by means of HLA analysis and blood typing. This gives us a suggestion that the genetic factors should be considered as a cause for the development of neoplasm, especially in case of fibroadenoma mammae.

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