Antidiabetic Effects of Ajoene in Genetically Diabetic KK-A^y Mice

Abstract

Antidiabetic effects of ajoene, derived from garlic, were investigated in genetically diabetic KK-A^y mice. Four-week-old male KK-A^y mice were kept on a laboratory diet containing 0.02 or 0.05% of ajoene for 8wk. The elevation of water intake was suppressed depending on ajoene intake. The levels of plasma glucose in the 0.05% ajoene-containing diet group was significantly suppressed to 73.8% compared with the control group at the 8th wk. Similarly, the plasma triglyceride level was significantly suppressed. It is suggested that hyperglycemia and hypertriglyceridemia are suppressed by ajoene treatment.

Journal

Journal of nutritional science and vitaminology   [List of Volumes]

Journal of nutritional science and vitaminology 51(5), 382-384, 2005-10  [Table of Contents]

The Vitamin Society of Japan

References:  12

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Codes

  • NII Article ID (NAID) :
    110002704092
  • NII NACSIS-CAT ID (NCID) :
    AA00703822
  • Text Lang :
    ENG
  • Article Type :
    NOT
  • ISSN :
    03014800
  • NDL Article ID :
    7681184
  • NDL Source Classification :
    ZR2(科学技術--生物学--生化学)
  • NDL Call No. :
    Z53-B484
  • DOI :
    10.3177/jnsv.51.382
  • Databases :
    CJP  NDL  NII-ELS  Journal@rchive