炭素源を違えて培養した<i>Rhizoctonia solani</i>の菌糸の生育およびトレハロース量に及ぼすバリダマイシンAの影響

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  • Effects of Validamycin A on the Growth of and Trehalose Content in Mycelia of Rhizoctonia solani Incubated in a Medium Containing Several Sugars as the Sole Carbon Source.
  • 炭素源を違えて培養したRhizoctonia solaniの菌糸の生育およびトレハロース量に及ぼすバリダマイシンAの影響〔英文〕
  • タンソゲン オ チガエテ バイヨウシタ Rhizoctonia solani

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Trehalose was the main sugar accumulated in the mycelia of Rhizoctonia solani and the trehalose content was 8% and more in dry weight mycelia irrespective of the sugar sources used for incubation. The addition of validamycin A (VM-A), an inhibitor of trehalases, increased the trehalose content even more. The inhibition of growth of the mycelia of R. solani by VM-A occurred when the fungus was incubated in a medium containing trehalose as the sole carbon source but not when incubated in a medium containing various sugars and carbohydrate polymers. The results indicated that trehalose was used as a storage molecule to supply glucose required for growth of R. solani and that the anti-fungal activity of VM-A resulted from the anti-trehalase activity of the chemical.

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