書誌事項
- タイトル別名
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- Mediastinal T Cell Type Lymphoblastic Malignant Lymphoma with Extremely High Adenosine Deaminase Activity in the Pleural Fluid.
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A 46-year-old Japanese man was referred to us for evaluation of a huge mediastinal tumor with bilateral massive pleural effusion. Histological examination of the specimen obtained with percutaneous needle biopsy from the mediastinal tumor demonstrated Tcell type lymphoblastic malignant lymphoma. The pleural fluid was sanguineous and included atypical mononuclear cells. Adenosine deaminase activity (ADA) in the pleural effusion was 963.2U/L, higher than ever reported. Serum ADA was 19.9U/L. Multiple combination chemotherapy successfully induced complete remission. Although it has been reported that ADA of the pleural fluid in lymphoproliferative disorders and other diseases could increase, a high level of ADA in the pleural fluid is generally utilized as a marker to distinguish tuberculous from nontuberculous effusions. Since activated or immature T lymphocytes produce ADA, the extremely high ADA in the pleural effusion in the present case was considered to originate from T cell type lymphoma cells. The authors emphasize that T cell type lymphoma may be one of the important causes when extremely increased levels of ADA in the pleural fluid are found.
収録刊行物
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- 肺癌
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肺癌 39 (2), 203-208, 1999
特定非営利活動法人 日本肺癌学会
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詳細情報 詳細情報について
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- CRID
- 1390282679654630400
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- NII論文ID
- 130003920283
- 110003114980
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- NII書誌ID
- AN00203978
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- ISSN
- 13489992
- 03869628
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- 抄録ライセンスフラグ
- 使用不可