Atypical Adenomatous Hyperplasia of the Lung Detected in a Thoracic CT Screening Program for Lung Cancer.

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  • 胸部ＣＴ検診にて発見された異型腺腫様過形成の検討

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Abstract

Objective: To examine the HRCT findings and the frequency of atypical adenomatous hyperplasia (AAH) of the lung detected by CT screening for lung cancer<BR>Subjects and Methods: During the period from April 1998 to November 1999, 7, 980 persons (men 6, 136, women 1, 844, average age, 57 years old) underwent CT screening for lung cancer with low dose spiral CT. All CT scans were obtained with a RADIX Turbo (Hitachi Ltd, Tokyo, Japan). Screening CT consisted of 10mm contiguous sections obtained with 120kVp and 50mA. HRCT with 2.0mm sections, 120kVp and 150mA were performed one month thereafter on those who were suspected to have lung cancer. A total of 5 cases of AAH were pathologically confirmed among 5, 991 initially screened subjects. These 5 cases are the basis of this study.<BR>Results: The size of AAH ranged in diameter from 7.9 to 12.4mm (mean, 9.8mm). All showed ground glass opacity on HRCT and none were visible on chest radiograph. Three cases did not change in size for 3-12 months. The frequency of AAH was 0.083% but it increased to 0.167% when cases suspicious on HRCT but not pathologically confirmed were included<BR>Conclusion: Thoracic CT screening using low dose spiral CT is useful for detecting AAH which can be a clue for diagnosing an early curable lung cancer.<BR>All HRCT images of AAH showed localized ground glass opacity on HRCT and no change during observation before surgery.

Journal

  • Haigan

    Haigan 41 (1), 21-25, 2001

    The Japan Lung Cancer Society

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