２ｃｍ以下の末梢型小型肺癌切除例の検討

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  • A Clinical Study in Small Sized Lung Cancer of Peripheral Type Less than 2cm in Diameter.

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Seventy-six patients with small peripheral type lung cancers underwent pulmonary resection in our hospital from 1972 to 1989. In all 76 patients, five-year survival rates were 77% for stage I, 71% for stage II, 36% for stage III, and 0% for stege N, respectively. Although tumors were less than 2cm in diameter, the course was poor in advanced cases (stage III, N).<BR>In small peripheral type lung cancers less than 2cm in diameter, pleural involvement, lymphatic invasion, vascular invasion and grade scars correlated significantly with the pathological stages.<BR>In this group, the tumor size of most advanced cases was from 1.6cm to 2cm, but in 2 patients it was less than 1.5cm in diameter.<BR>The mean age of 12 cases with advanced cancer was 53 years old and reason for detection was symptomatic in 6 cases. Histologically, 11 patients had adenocarcinoma and one had small cell carcinoma.<BR>DNA ploidy was analyzed by flow cytometry in 8 advanced cases. Four cases showed diploidy and 4 cases showed aneuploidy, but no relationship with their course was recognized.<BR>Concerning the reason for classification as stage III or IV, 5 patients were N2, 5 patients had pulmonary metastasis and 4 patients had pleural dissemination.

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  • 肺癌

    肺癌 32 (6), 869-875, 1992

    特定非営利活動法人 日本肺癌学会

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