インスリンおよびグルコースの投与に対するコイ肝膵臓の酵素活性ならびに代謝中間体濃度の応答

DOI NDLデジタルコレクション 日本農学文献記事索引 Web Site 被引用文献3件 参考文献19件

書誌事項

タイトル別名
  • Response of Hepatopancreatic Enzyme Activities and Metabolic Intermediate Concentrations to Bovine Insulin and Glucose Administration in Carp Cyprinus carpio.
  • 魚類糖代謝の調節　ＸＸＸＩＩＩ　　インスリンおよびグルコースの投与に対するコイ肝すい臓の酵素活性ならびに代謝中間体濃度の応答
  • インスリン オヨビ グルコース ノ トウヨ ニ タイスル コイ カンスイゾウ ノ コウソ カッセイ ナラビニ タイシャ チュウカンタイ ノウド ノ オウトウ

この論文をさがす

抄録

The responses of hepatopancreatic enzyme activities and metabolic intermediate concentrations to bovine insulin and glucose administration were examined in carp Cyprinus carpio. An intraperitoneal insulin injection significantly decreased the concentrations of serum glucose and amino acids in the fish. The insulin injection increased activities of hepatopancreatic phosphofructokinase (PFK) and G6PDH as well as concentrations of hepatopancreatic F6P, AMP, and ADP, while it decreased activities of FBP ase and G6Pase. These results suggest that the insulin injection enhanced in vivo glycolysis through the activation of PFK. It was also suggested that PFK was activated by the conformation change of PFK as well as changes in concentrations of metabolic intermediates in hepatopancreas rather than the induction of PFK. On the other hand, the oral glucose administration rapidly increased serum glucose concentration, but the enzyme activities and metabolic intermediate concentrations were not much affected at 2 hours after glucose administration. However, they were shifted to a pattern similar to that of insulin injection at 6 hours after glucose administration. This may indicate that glucose administration also activated hepatopancreatic glycolysis through an increased secretion of insulin with a short time lag.

収録刊行物

  • 日本水産学会誌

    日本水産学会誌 65 (5), 896-900, 1999

    公益社団法人 日本水産学会

被引用文献 (3)*注記

もっと見る

参考文献 (19)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ