Fibronectin-like immunoreactive structures in embryonic rat brain.

DOI NDLデジタルコレクション Web Site

この論文をさがす

抄録

Fibronectin immunocytochemistry applied in trypsin-treated sections of embryonic rat brain revealed several positive structures. These include, in 18-day-embryo for example, somata of neuroblasts, ependymal cells, developing nerve terminals, meninges and blood vessels. Without trypsin treatment no positive immunoreactivity was seen in neural elements, though weak staining was observed only in meninges and capillaries. The neuroblasts possessing intracytoplasmic immunoreactivity for fibronectin were distributed in particular brain regions such as the cortical plate of the cerebrum and the primordium of the cerebellar nuclei. The intensity of immunostaining in neuronal and vascular structures gradually decreased or diminished at around perinatal periods. The results suggested that fibronectin may have important roles in neuronal migration or maturation. Moreover, fine positive processes ramified from capillaries suggested the role of fibronectin in neovascularization.

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ