吸着療法における安全性と副作用(<特集>アフェレシスにおけるセイフティーマネジメント)  [in Japanese] Safety and Complication of Adsorption Treatment in Apheresis Therapy  [in Japanese]

In the field of apheresis therapy, various kinds of adsorbents of good biocompatibility with a specific removal of pathological molecules have been developed. Plasma adsorption which separates plasma from the blood and adsorbs pathological molecules used to be the mainstream of apheresis treatment. Recently, direct hemoperfusion has become widely accepted because of the weaker influence on the blood cells and the ease and simplicity of operation compared to those of plasma adsorption. We introduce the various kinds of adsorbents (excluding the granular leukocyte removal) including the newly recognized adsorbents and describe their safety and the points to notice.