Comparative Evaluation of Efficacy in Platelet Collection Using Three Apheresis Systems and Status of Platelet Transfusion

Platelet concentrate product-derived plateletapheresis from a single donor is preferable in order to reduce the risks of adverse reactions by platelet transfusion. Plateletapheresis should be effectively and sufficiently carried out to collect larger units of platelet concentrate products. This study evaluated the comparison on efficacy of three plateletapheresis systems and the status of platelet transfusion. Using three apheresis systems (Amicus Single needle ; Amicus-S, Amicus Double needle ; Amicus-D, and CCS), 653 platelet collections were performed at Akita Red Cross Blood Center. Pre-procedure platelet count, hematocrit of donors, procedure time, volume processed, platelet yields, and platelet recovery rates were evaluated and compared. The average units of platelet concentrate and the number of donors transfused per patient were evaluated in Akita University Hospital. Pre-procedure platelet count and hematocrit of donors were comparable among three systems. Platelet yields were 3.3×10^<11>, 3.5×10^<11>, and 2.8×10^<11>/bag, for Amicus-S, Amicus-D, and CCS, respectively. Volume processed was less in CCS ; however, procedure time was longer in CCS compared with Amicus-S and Amicus-D. Platelet recovery rates were comparable among three systems. The average number of donors of platelet product per patient has recently reached nearly 1.0 and more than 90% of patients receive platelet product derived from a single donor. Characteristics of each apheresis system should be considered and a suitable system is to be assigned according to the donor's conditions including the donor's time flexibility.