Study on Elemental Technologies for Creation of Healthcare Chip Fabricated on Polyethylene Terephthalate Plate
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- OKI Akio
- the Department of Materials Science, The University of Tokyo
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- TAKAMURA Yuzuru
- the Department of Materials Science, The University of Tokyo
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- FAKASAWA Takayuki
- the Department of Materials Science, The University of Tokyo
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- OGAWA Hiroki
- the Department of Materials Science, The University of Tokyo
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- ITO Yoshitaka
- Research & Development Center, Shindengen Kogyo Corp.
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- ICHIKI Takanori
- the Department of Electric and Electronic Engineering, Toyo University
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- HORIIKE Yasuhiro
- the Department of Materials Science, The University of Tokyo
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Abstract
Elemental technologies have been studied to establish the healthcare chip which is an intelligent micro analytical system to detect human health markers from a trail of blood. A two steps process for deep quartz dry-etching was discussed in order to overcome the issues of concave-shaped defects at the bottom of grooves. A coating with 2-methacryloyloxyethylphosphorylcholine (MPC) polymer was studied to suppress the adsorption of bio-substance onto the inner wall of the flow channel on chip and good bio-compatibility was achieved for suppression of protein adsorption and blood cell adhesion. A prototype of healthcare chip was fabricated on polyethylene terephthalate (PET) plate using a micro molding technique. Using this chip, the ion concentrations of pH, Na^+, K^+, Ca^<++> were successfully measured with embedded ion sensitive field effect transistors (ISFET's).
Journal
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- IEICE TRANSACTIONS on Electronics
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IEICE TRANSACTIONS on Electronics 84 (12), 1801-1806, 2001-12-01
The Institute of Electronics, Information and Communication Engineers
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Details 詳細情報について
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- CRID
- 1573105977302481024
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- NII Article ID
- 110003212120
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- NII Book ID
- AA10826283
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- ISSN
- 09168524
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- Web Site
- http://hdl.handle.net/10119/4727
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- Text Lang
- en
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- Data Source
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- CiNii Articles