9. Optimizing Filters Used in Tomographic Brain Perfusion Imaging

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Brain perfusion imaging has become an important study that is being done in Nuclear Medicine departments today. The results of the scan plays a role in the management of the patient. Therefore, it is imperative that we obtain the best images that we can for the physicians to interpret. The factors that can affect the quality of a brain scan are many. Positioning, radiopharmaceuatical quality, time of injection, acquisition parameters, post acquisition processing, are but a few. Most of these parameters have been addressed in other papers and will not be addressed here. This paper will look at optimizing the filters used brain perfusion imaging. The research on this topic has not been completed yet, so specific details are not available at this time. What we will be doing is using a brain phantom which represent one slice in the transaxial projection. We will image the phantom using 360 degree acquisition using a rotating gamma camera. The phantom will be normalized to the same slice in a patient study to better simmulate the patient situation. We will look at the von Hann filters as well as various Butterworth filters using different cut-off frequencies. We may than submerse the phantom in water or wheat to simmulate the scatter from the skull.

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