Studies on the Constituents Mikania hirsutissima (Compositae)

Abstract

Two novel norhumulene-type sesquiterpenes, named mikaniahumulene I (1) and II (2) were isolated along with nine known compounds, seven kaurenic acid-type diterpenes (3-9), a coumarin (10) and a flavone (11), from the aerial parts of Mikania hirsutissima DC (Compositae). The structures of new norhumulenes were determined by spectroscopic means. The cytotoxic activities of isolated compounds against leukemia cells (L 1210) were investigated; among the isolated compounds, 1,5,8,and 11 showed relatively strong cytotoxicity.

Journal

Chemical & pharmaceutical bulletin   [List of Volumes]

Chemical & pharmaceutical bulletin 47(10), 1436-1438, 1999-10-15  [Table of Contents]

The Pharmaceutical Society of Japan

References:  10

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Codes

  • NII Article ID (NAID) :
    110003617109
  • NII NACSIS-CAT ID (NCID) :
    AA00602100
  • Text Lang :
    ENG
  • Article Type :
    ART
  • ISSN :
    00092363
  • NDL Article ID :
    4880991
  • NDL Source Classification :
    ZS51(科学技術--薬学) // ZP1(科学技術--化学・化学工業)
  • NDL Call No. :
    Z53-D167
  • Databases :
    CJP  NDL  NII-ELS 

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