Synthese de dihydro-6,7 5H-pyrimidino(5,4-c)carbazoles et de 7H-pyrimidino(5,4-c)carbazoles.

• LANCELOT JEAN-CHARLES

• GAZENGEL JEAN-MARIE

• ROBBA MAX

Abstract

The synthesis of 6, 7-dihydro-5H-pyrimidino[5, 4-c]carbazoles (3) was achieved by cyclisation of 1, 2, 3, 4-tetrahydrocarbazol-4-ones with triformamidomethane. The oxydation with potassium permanganate of 6, 7-dihydro-5H-pyrimidino[5, 4-c]carbazoles gave the 7H-pyrimidino[5, 4-c]carbazoles (4). The reactions of the pyrimidinocarbazoles (4a) and (4e) with lithium organic compounds afforded 4-substituted derivatives (6). The structure of the derivatives was determined by ¹H-NMR and Overhauser effect.

Journal

• Chemical and Pharmaceutical Bulletin

  Chemical and Pharmaceutical Bulletin 31 (8), 2652-2661, 1983

  The Pharmaceutical Society of Japan

Keywords

• Overhauser effect

Details

• CRID: 1390001204165127808
• NII Article ID: 110003624471
• NII Book ID: AA00602100
• DOI: 10.1248/cpb.31.2652
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/31/8/31_8_2652/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1985042841
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed