OXIDATION OF 1,3-DIMETHYL DERIVATIVES OF PYRIMIDINE BASES WITH m-CHLOROPERBENZOIC ACID

Abstract

Oxidation of 1,3-dimethylthymine (1), 1,3-dimethyluracil (2), and 5-fluoro-1,3-dimethyluracil (3) with m-chloroperbenzoic acid were investigated. 1 gave the cis diol 5,6-dihydrothymine derivative (4) stereoselectively. Its stereostructure was definitely determined by an X-ray analysis. 2 afforded 7,8,and 9,and 3 afforded 8.

Journal

Chemical & pharmaceutical bulletin   [List of Volumes]

Chemical & pharmaceutical bulletin 32(5), 2056-2058, 1984-05-25  [Table of Contents]

The Pharmaceutical Society of Japan

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Codes

  • NII Article ID (NAID) :
    110003625021
  • NII NACSIS-CAT ID (NCID) :
    AA00602100
  • Text Lang :
    ENG
  • ISSN :
    00092363
  • Databases :
    NII-ELS 

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