Studies on the Constituents of Momordica cochinchinensis SPRENG. II. Isolation and Characterization of the Root Saponins, Momordins I, II and III

• IWAMOTO M.

  Faculty of Pharmaceutical Sciences, Fukuoka University

• OKABE HIKARU

  Faculty of Pharmaceutical Sciences, Fukuoka University

• YAMAUCHI TATSUO

  Faculty of Pharmaceutical Sciences, Fukuoka University

Abstract

From the root of Momordica cochinchinensis SPRENG. (Cucurbitaceae), three saponins named momordins I, II and III have been isolated. Their structures were determined on the basis of chemical and spectral evidence as oleanolic acid 3-O-α-L-arabinopyranosyl (1→3)-β-D-glucuronopyranoside (momordin I), 28-O-β-D-glucopyranoside of momordin I (momordin II) and 3β-hydroxy-11α, 12α-epoxy-olean-28,13-olide 3-O-α-L-arabinopyranosyl (1→3)-β-D-glucuronopyranoside (momordin III). Momordin II was proved to be identical with hemsloside Ma_1 isolated from the tubers of Hemsleya macrosperma and H. chinensis.

Journal

• Chem. Pharm. Bull.

  Chem. Pharm. Bull. 33 1-7, 1985

  The Pharmaceutical Society of Japan

Keywords

• Momordica cochinchinensis
• Cucurbitaceae
• pentacyclic triterpene glycoside
• glucuronide saponin
• bisdesmoside
• oleanolic acid
• 3β-hydroxy-11α, 12α-epoxy-olean-28, 13-olide

Details

• CRID: 1574231877205622016
• NII Article ID: 110003625093
• NII Book ID: AA00602100
• ISSN: 00092363
• Web Site: https://search.jamas.or.jp/link/ui/1985142228
• Text Lang: en
• Data Source:
  • CiNii Articles