Oxidative 1,2-Aryl Migration of Alkyl Aryl Ketones by Using Diacetoxyphenyliodine : Syntheses of Arylacetate, 2-Arylpropanoate, and 2-Arylsuccinate

• 田村 恭光

  Faculty of Pharmaceutical Sciences, Osaka University

• 矢倉 隆之

  Faculty of Pharmaceutical Sciences, Osaka University

• 城内 善昭

  Faculty of Pharmaceutical Sciences, Osaka University

• 春田 純一

  Faculty of Pharmaceutical Sciences, Osaka University

抄録

Oxidative 1,2-aryl migration of alky aryl ketones (2,5,and 8) to 2-arylalkanoates (3,6,and 9) was effected by using diacetoxyphenyliodine (1). The migration was successfully applied to the preparation of the antiinflammatory agents ibuprofen (15) and clidanac (17).

収録刊行物

• Chem. Pharm. Bull.

  Chem. Pharm. Bull. 33 1097-1103, 1985

  公益社団法人日本薬学会

キーワード

• diacetoxyphenyliodine
• oxidative 1, 2-aryl migration
• methyl 2-arylalkanoate
• dimethyl 2-arylsuccinate
• 2-arylalkanoic acid
• 2-arylsuccinic acid
• antiinflammatory agent
• ibuprofen
• clidanac

詳細情報

• CRID: 1572543027345238528
• NII論文ID: 110003625489
• NII書誌ID: AA00602100
• ISSN: 00092363
• Web Site: https://search.jamas.or.jp/link/ui/1986011354
• 本文言語コード: en
• データソース種別:
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