Application of Double-Reciprocal Plot between the Shift-Length of Absorption Maxima of Solubilized Alkylparabens and Sodium Dodecyl Sulfate Concentration to the Determination of the Distribution Parameter

Abstract

In this paper, we discuss the reason why plots of the reciprocal of ([sodium dodecyl sulfate]-cmc) against the reciprocal of the shift-length of the absorption maxima of solubilized alkylparabens show linearity, and what information can be derived from the straight line. Extrapolation of the double-reciprocal plot was utilized to obtain the maximum value of the shift-length, which can not be measured directly. The average of the distribution parameter values can be obtained from the slope of the plot.

Journal

Chemical & pharmaceutical bulletin   [List of Volumes]

Chemical & pharmaceutical bulletin 34(11), 4862-4865, 1986-11-25  [Table of Contents]

The Pharmaceutical Society of Japan