Antitumor Activity of Hypsizigus marmoreus. I. Antitumor Activity of Extracts and Polysaccharides

• 池川 哲郎

  National Cancer Center Research Institute

• 斉藤 英晴

  National Cancer Center Research Institute

• 馮 威健

  National Cancer Center Research Institute

• 張 恵玲

  National Cancer Center Research Institute

• 李 蘭芳

  National Cancer Center Research Institute

• 松沢 恒友

  Nagano Prefectural Research Institute of Rural Industry

抄録

Antitumor activity of Hypsizigus marmoreus, one of the most popular Japanese edible mushrooms, was investigated. The aqueous and methanol extracts were tested against allogeneic tumor, solid sarcoma 180 and syngeneic tumor, Meth A fibrosarcoma. The aqueous extract was highly active in inhibiting growth of solid sarcoma 180,but not as much for Meth A fibrosarcoma. Fractionation of antitumor substances of the aqueous extract isolated four polysaccharides. Chemical analysis revealed one of them to be β-(1-3)-glucan with a remarkable inhibitory effect against tumor-growth of sarcoma 180.

収録刊行物

• Chem. Pharm. Bull.

  Chem. Pharm. Bull. 40 (7), 1954-1957, 1992

  公益社団法人日本薬学会

キーワード

• antitumor activity
• mushroom
• Basidiomycetes
• Hypsizigus marmoreus
• sarcoma 180
• Meth A fibrosarcoma
• polysaccharide

詳細情報

• CRID: 1571135652347214720
• NII論文ID: 110003630126
• NII書誌ID: AA00602100
• ISSN: 00092363
• Web Site: https://search.jamas.or.jp/link/ui/1994047765
• 本文言語コード: en
• データソース種別:
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